RAN and cancer: The hTC (Fig. 8, 2nd set of bars) and Brms1 (Fig. 8, last set of bars) promoters also displayed cancer specificity in the form of significantly higher GFP expression in all cancer cells when compared with normal BJ cells, while − 279/+ 5 and Ran showed specificity in Skov3 and Ovcar3 but not Kuramochi cells (Fig. 8).