GFAP and Menkes disease: In male rats, MS and MD resulted in decreased GFAP reactivity and reduced cytoskeletal complexity in the hippocampus (Roque, Ochoa‐Zarzosa, & Torner, 2016; Saavedra, Fenton Navarro, & Torner, 2018) and cortex (Musholt et al., 2009) within 24 hr after MS or MD.