APOE and Alzheimer disease: Finally, using machine learning approaches, we assessed the diagnostic information content of these MEG-derived static connectivity matrices by quantifying their accuracy in solving three problems: 1) Whether young APOE-ε4 carriers could be distinguished from young non-carriers, 2) Whether AD patients could be distinguished from elderly controls and 3) Whether a classifier trained on identifying young E4 carriers could identify AD patients, purely from their MEG connectivity matrices.