However, our analysis revealed that the decrease in 25(OH)D concentrations in dogs with babesiosis was independent of serum creatinine and ALT, thereby suggesting that the effect of renal insufficiency or liver damage was unlikely to be responsible for development of hypovitaminosis D. Moreover, our analysis revealed that hypovitaminosis D was not significantly correlated with the time from the last meal. Here, GPT is linked to Renal insufficiency.