For instance, lncRNA HOXD‐AS1 promotes osteosarcoma by recruiting the enhancer of zeste homolog 2 (EZH2), which binds to the promoter of P57 to inhibit p57 expression.6 LncRNA HCP5 functions as a ceRNA of miR‐22‐3p, miR‐186‐5p and miR‐216a‐5p, which activate ST6GAL2 and promote the development of follicular thyroid carcinoma.7 Here, EZH2 is linked to osteosarcoma.