Based on the increased frequencies of tumor-reactive T cells in DMXAA-treated tumors and data in the literature documenting the importance of DCs to STING-driven anti-tumor responses [36, 59], we hypothesized that DCs in the DMXAA-treated PDA microenvironment are mature and play a role in the accumulation of T cells. Here, STING1 is linked to Patent ductus arteriosus.