PFS of the patients with PIK3CA mutant glioblastoma (6.1 months) was significantly shorter than that of patients with the wildtype counterpart (9 months) (p = 0.008) (Additional file 5: Figure S5), while OS was not significantly different (median 13.1 months vs. 13.3 months, p = 0.40). This evidence concerns the gene PIK3CA and glioblastoma.