Interestingly, in Ep/non-CSC transduced to express constitutive SNAIL, we found that sustained IFNβ treatment repressed SNAIL-mediated CSC properties (partial reversion of CD44 and repressed tumor sphere initiation capacity) while partially reducing steady-state levels of SNAIL protein (Additional file 1: Figure S6A-C). The gene discussed is CD44; the disease is neoplasm.