IFNA1 and neoplasm: In contrast to the CSC-inducing effects of OSM, recent evidence has demonstrated that patients with TNBC harboring elevated numbers of tumor-infiltrating lymphocytes (TILs) and endogenous IFN/signal transducer of activated transcription 1 (STAT1) signaling have an improved therapeutic response and prognosis compared to patients with low TILs and IFN/STAT1 signaling [9–11].