AKT1 and breast cancer: We found that some of the top-25 ranked pathways in breast cancer data are related to at least one of six functions, such as the Ras signaling pathway (KEGG ID: hsa04740), Necroptosis (KEGG ID: hsa04217), Regulation of actin cytoskeleton (KEGG ID: hsa04810), and the PI3K-Akt signaling pathway (KEGG ID: hsa04151) [34].