BARD1 and breast cancer: In the subgroup of 818 index patients with BC and at least one relative with OC (mean AAD 50.1 years; range 17–92 years), 4 index patients carried heterozygous germline LoF variants in BARD1 (carrier frequency = 0.49%) and an OR of 5.08 (95% CI = 1.81–14.31; P = 0.01046) compared with all control individuals.