Several chemokines (CCL2, CCL5, CXCL1, CXCL10 and CXCL12) produced by tumour and stromal cells activate their specific mast cell receptors (CCR2, CCR3, CXCR2, CXCR3 and CXCR4), which are important for TAMC localization in TME [49,79,110,111,112,113,114,115,116]. Here, CXCL12 is linked to neoplasm.