Increased phosphorylation of (mTOR) substrate, p70 ribosomal subunit 6 kinase 1 (S6K1) along with the high expression of mTOR regulator, and the serine/threonine protein kinase (Akt) was also observed in lymphocytes and brain tissues derived from subjects with FXS [136]. This evidence concerns the gene MTOR and fragile X syndrome.