The rs4143815-PDL1 has been previously proposed as a potential biomarker of gastric adenocarcinoma risk [19] and of NSCLC risk [20], and as a potential prognostic biomarker of OS in patients affected by NSCLC, lung adenocarcinoma, and squamous cell carcinoma who underwent curative surgical resection [21,22]. This evidence concerns the gene CD274 and non-small cell lung carcinoma.