We also excluded the following history of complications within 2 years: tense ascites (paracentesis: C8050, C8051, and Q2470), variceal bleeding (variceal ligation: Q2430-Q2438, Q7631-Q7634), any vasoactive drug (octreotide, vasopressin, terlipressin, or somatostatin), hepatic encephalopathy (lactulose enema: M0076), and hepatorenal syndrome (co-administration of terlipressin and albumin). This evidence concerns the gene SST and Renal insufficiency.