Based on a chromatin immunoprecipitation (ChIP)-Seq database search from the University of California Santa Cruz (UCSC) Genome Browser (http://genome.ucsc.edu), the enrichment of YY1 at the BCCIP transcriptional start site (TSS) proximal region in several cancer cells including A549 lung cancer cells, HepG2 human hepatocellular carcinoma cells, and HCT116 human colon cancer cells was found, suggesting the function of YY1 in regulating BCCIP gene transcription. The gene discussed is YY1; the disease is malignant colon neoplasm.