TNF and alkaline phosphatase measurement: We examined serum IL-6 and TNF-αlevels, and the results showed a significantly enhanced level of IL-6 and TNF-α in the cerulein-induced pancreatitic models, and this was significantly reduced in TMP-treated mice (Figure 2(a)).These data demonstrate that TMP inhibits serum TNF-α and IL-6 levels in cerulein-induced AP in mice.