SLC12A1 and Schnyder corneal dystrophy: The present studies were undertaken to determine the effects of SCD on vasopressin, aquaporin2 (AQP2), urea transporter A1 (UTA1), Na‐K‐Cl co‐transporter 2 (NKCC2), epithelial Na channels (ENaC), aquaporin1 (AQP1), nuclear factor of activated T cells 5 (NFAT5) and Src homology region‐2 domain‐containing phosphatase‐1 (SHP‐1), an important regulator of NFAT5, in the Berkeley SCD mouse kidney medulla.