MAPK8 and Pallister-Hall syndrome: The mitogen‐activated protein kinases (MAPKs, including JNK, ERK and p38 MAPK) have been proposed to play critical roles in maintaining lipid homeostasis.21, 22, 23 Therefore, to delineate the cellular and molecular mechanisms underlying bromide‐induced alleviation of FFA‐triggered excessive lipid accumulation in mouse PHs, we evaluated the effect of bromide on the phosphorylation of MAPK signalling cascades.