FTO and obesity due to melanocortin 4 receptor deficiency: The analysis of single‐variants revealed that seven variants reached a statistically significant association with BD (p < 0.05); these BD‐associated variants were mapped to intron 2 of RPGRIP1L, FTO upstream region and intron 1 promoter flanking of FTO. When we considered obesity (BMI > 30 kg/m2) as phenotype, 14 variants in the promoter flanking region immersed in FTO intron 1 reached a statistically significant association (p < 0.05).