Analyzing FOXP1 (variants associated with obesity could disturb the binding site of this TF) has been previously associated with speech development, and deleterious genetic variants are known to cause FOXP1 syndrome (Siper et al., 2017); patients with this syndrome have psychiatric alterations and almost 30% of them are obese (Le Fevre et al., 2013; Lloveras et al., 2014), suggesting a possible link between FOXP1 and obesity. This evidence concerns the gene FOXP1 and obesity due to melanocortin 4 receptor deficiency.