GLP1R and obesity due to melanocortin 4 receptor deficiency: GLP‐1 and the ability of its analogues to increase insulin secretion and control blood glucose levels, as well as their anti‐obesity effects, have been widely explored.20, 28, 29, 30 However, the potential for IL‐6 to act as a downstream signalling peptide of GLP‐1 has not yet been fully explored.