AFP and neoplasm: According to the subgroup analyses depending on tumour size, HCC subjects with a tumour size ≤5.0 cm have higher 5hmC content and lower levels of fasting plasma aspartate aminotransferase, the ratio of alanine aminotransferase to aspartate aminotransferase, c‐glutamyl transferase and AFP in comparison with the patients with tumour size ≥5 cm.87