TET1 and hepatocellular carcinoma: Not only can TET1 be modulated by microRNAs, but TET1 can also induce several invasion‐suppressor microRNA genes through DNA demethylation in their proximal CpG locus.49, 55, 58 Hence, it is difficult but necessary to investigate the relevant regulatory machineries that orchestrate transcriptional and/or post‐transcriptional regulation during the initiation and progression of HCC.