MYC and cancer: Analysis of the TCGA (the cancer genome atlas) pan-cancer cohort of lung adenocarcinoma (LuAd) revealed amplification and/or overexpression of c-MYC in up to 20% of LuAd and a significant enrichment for MYC overexpression in KRAS mutant tumours (p = 0.025) (Figure 1A and Figure S2).