HOTTIP and head and neck squamous cell carcinoma: Using |logFC| ≥1 and p<0.05 as the cutoff criteria, a total of 891 differentially expressed genes (DEGs) were identified including 723 upregulated genes and 168 downregulated genes in HOTTIP high expressed HNSCC tissues compared to HOTTIP low expressed HNSCC tissues (Figure 7(a)).