It was noteworthy that a three-lncRNA signature (KTN1-AS1, LINC00460, and RP5-894A10.6) derived from the Atlas of ncRNA in cancer database could predict the survival of HNSCC patients, and a three-lncRNA signature (RP11-366H4.1.1, LINC00460, and AC093850.2) could predict overall survival and disease-free survival in patients with esophageal squamous cell carcinoma [25, 27]. This evidence concerns the gene KTN1 and head and neck squamous cell carcinoma.