Linear regression analysis showed a strong correlation between log-transformed CRP and sP2X7R in the ischemia subgroup (R2 linear = 0.645), and a weaker correlation in the infectious disease subgroup (R2 linear = 0.176), while there was basically no correlation in the cancer (R2 = 0.004) and “others” (R2 = 0.12) sub-groups (Figure 2C). Here, CRP is linked to cancer.