IFNB1 and infection: Additionally, in this mouse line the IFNβ coding sequence is flanked by loxP sites (IFN-βfloxβ−luc/floxβ−luc) providing the possibility to characterize the impact of IFNβ production by a given cell type on the pathophysiology of various infections via tissue- or cell-specific Cre-mediated deletion of IFNβ (60).