MSC/fibroblast-derived chemokines, including murine CXCL1 and CXCL2 (counterparts of human CXCL8), CCL2 and CCL5 were associated with recruitment of neutrophils, tumor-associated macrophages and myeloid-derived suppressor cells to TNBC tumors, where they promoted disease course (22, 25, 63, 65). This evidence concerns the gene CXCL2 and neoplasm.