In addition to nradd, which is expressed in the mouse hypothalamus (29), ccm2, map2k3, and genes from the Smith-Magenis syndrome region in the human genome associate with met1. ccm2 is associated with neurovascularization (30) while map2k3 was recently identified as a superior memory candidate gene in SuperAgers (31). Here, CCM2 is linked to Smith-Magenis syndrome.