Given the fact that survivin is a prognostic marker in many cancers, it seems that there are some therapeutic implications which need to be worked upon in relation to conventional chemotherapy (Kim et al., 2010) .Therefore, we compared the prevalence of -31 SNP of survivin in oral cancer patients and normal healthy adults with no prior history or family history of cancer. Here, BIRC5 is linked to lip and oral cavity carcinoma.