AKT1 and breast carcinoma: Phosphatidylinositol 3- kinase/AKT/ mammalian target of rapamycin(PI3K/AKT/mTOR) pathway is dysregulated in various cancer along with the breast cancer and is the major signaling pathway which controls the routine activity of our body including cell survival, cell division, etc. In this study, we found many pre-existing compounds against the mTOR protein and technically found SF1126 with the high-affinity properties along with the best binding energy score.