The current standard work-up of Non Small Cell Lung Cancer (NSCLC) patients includes the search for sensitizing mutations of EGFR gene (Sharma et al. 2007; Riely et al. 2006; Rosell et al. 2010; Mok et al. 2009) that allowed identification of patients eligible for treatment with an EGFR tyrosine kinase inhibitor (TKI) (Singh & Jadhav 2018). This evidence concerns the gene EGFR and non-small cell lung carcinoma.