On the other hand, the performance of NF-light levels in discriminating AD from CNS was similar to that of classical AD biomarkers (ROC analysis: AUC=0.830, AD vs. CNS) (Fig. 4A), whereas a better performance than Aß42, t- and p-tau and IATI (a parameter combining Aß42 and t-tau) was observed in differentiating TP patients from CNS (ROC analysis: AUC=0.873, TP vs. CNS) (Fig. 4B). Here, MAPT is linked to Alzheimer disease.