Every 1 kg of additional birthweight was shown to yield 2.620 mmol/L lower 2h-postprandial glucose, 3.297% lower glycated albumin, 1.031% lower glycated hemoglobin, 0.769 mmol/L lower total cholesterol and 0.627 mmol/L lower LDL-C levels after adjustment for age, gender and BMI, the conclusion remained the same after further adjustment for the duration of diabetes. The gene discussed is ALB; the disease is diabetes mellitus.