The figure shows that the items of both PROMs are well targeted to the RA patients in the present study; Reliability is highest for frequently occurring levels of fatigue/disease impact and the majority of patients in the present samples had a reliable score (i.e., conditional reliability > 0.70) for both the BRAF-MDQ (92%) and RAID (95%). The gene discussed is BRAF; the disease is rheumatoid arthritis.