TYR and melanoma: As expected, the majority of cells annotated by both Tirosh et al. as ‘malignant cells’ and by scMatch as melanocytic expressed high levels of the melanocytic markers MITF, PMEL, MLANA and TYR. Additionally 90 of the 132 cells labelled as ‘unresolved’ in the original publication, and 86 of the 416 cells labelled as ‘non-malignant cells’ were classified as melanoma cells or melanocytes by scMatch, the majority of which expressed melanocytic markers.