Recently, the polypyrimidine tract-binding protein 1 (PTPBP1) splicing repressor has been implicated in the regulation of alternative splicing of FGFR1α and FGFR1β. The study conducted in breast cancer cells revealed that PTBP1 represses the splicing of FGFR1β [138]. The gene discussed is PTBP1; the disease is breast carcinoma.