TRPA1 and Hyperglycemia: Similar results were obtained in experiments where two other TRPA1 agonists (i.e., N-methylmaleimide (i.e., NMM), an oxidizing agent that forms a covalent bond with TRPA1 and methylglyoxal (i.e., MG), a reactive molecule and an endogenous TRPA1 agonist, produced during hyperglycemia) were used.