Additionally, immunohistochemical analysis of GBM tumor tissues demonstrated that only a few integrin α10β1-expressing GBM cells (between 0‒10% in different patient samples) were co-expressed with Nestin, and even fewer of the integrin α10β1-expressing GBM cells were co-expressed with Sox2 (Figure 3B). The gene discussed is SOX2; the disease is glioblastoma.