A number of reports have described HLXB9 overexpression in malignancies other than leukemia, including breast cancer [43,44], prostate cancer [45], bladder cancer [46], colorectal cancer [47], liver cancer [48], neuroblastoma [28], and pancreatic tumors [49], making HLXB9 an interesting gene in cancer biology. The gene discussed is MNX1; the disease is liver cancer.