Compared with the control group, which had a mean normalized SNCA mRNA expression level of 17.4 ± 5.4 in their blood cells, MDD patients in the BLADe and ADT studies displayed increased SNCA mRNA expression levels (mean normalized expression of 31.9 ± 15.3 and 24.3 ± 13.8, respectively; analysis of variance (ANOVA) df = 2, F = 5.9, p = 0.004; Table 2). The gene discussed is SNCA; the disease is major depressive disorder.