On magnetic resonance imaging, the tumor was isointense relative to the brain and enhanced on T1-weighted imaging.[5,7,9] Unlike multiple myeloma, solitary skull plasmacytomas may not have serum M protein or Bence Jones light chains in the urine.[3,5,7,9] The diagnosis is usually made after pathologic tissue is obtained after surgery. This evidence concerns the gene MYOM2 and plasma cell myeloma.