MUTYH and uterine cervix carcinoma in situ: Several well-defined phases of cervical carcinoma have been described, including precursor lesion cervical intraepithelial neoplasia (CIN) and malignant carcinoma.[32] Data from the current study showed that the homozygous CAC/CAC genotype at position 324 of MUTYH is associated with significant risk of CIN III (OR = 1.94) and CSCC (OR = 3.83).