MB and rhabdomyolysis: This disruption of skeletal muscle integrity leads to the direct release of intracellular muscle components, including myoglobin, creatine kinase (CK), aldolase and lactate dehydrogenase, as well as electrolytes, into the bloodstream and extracellular space.[1,2] Acute rhabdomyolysis has been described during primary HIV infection, and also as an adverse reaction to certain drugs, including antiretroviral therapy (ART).[3] At this time, we present an interesting case of rhabdomyolysis suspected to be associated with Triumeq, a side effect rarely described while receiving this ART combination.