However, knocking out SynGAP protein in the adult hippocampus causes memory impairments (Muhia et al., 2012) and increases seizure susceptibility (Ozkan et al., 2014), suggesting that Syngap1 may also have unique, non-developmental functions in the adult brain that promotes cognitive function and suppresses neural excitability. The gene discussed is SYNGAP1; the disease is memory impairment.