INS and Insulin resistance: It has been shown that visceral obesity and ectopic fat deposit can increase the risk of insulin resistance and inflammatory factors.29-31 In this regard, compared with MHL phenotype, MUHL individuals have shown reduced compensatory insulin response.32 Previous studies have reported that physical activity increased the likelihood of promoting metabolic health status.33 Further, MUHL subjects proved to have higher levels of hs-CRP, where this condition is significantly associated with high levels of blood sugar and lipids.28