In addition to the genes mentioned above, IFI44L was found to be a hypomethylated type I IFN-related gene in the autoimmune diseases in this work, as well as in primary Sjögren’s syndrome (Imgenberg-Kreuz et al., 2016), although it was not annotated by GO in type I IFN-associated terms. Here, IFI44L is linked to autoimmune disease.