We found that the frequency of intermediate monocytes was inversely correlated with the frequency of Foxp3+CD25+CD45RA+ Tregs and Foxp3+Helios+CD45RA+ Tregs in the CHI group (Figure 3A) and the CHI&RPR+ group (Figure 3B). Here, EXTL3 is linked to congenital isolated hyperinsulinism.