Cytokine measurements in CD73+ B16F10 wildtype tumor lysates grown on CD73−/− mice revealed a down-regulation of pro-inflammatory cytokines [Granulocyte-macrophage colony-stimulating factor (GM-CSF) and IFN-γ] and enhanced expression of anti-inflammatory/pro-angiogenic cytokines (IL-4, IL-10, IL-13, M-CSF) (248). Here, IFNG is linked to neoplasm.