Moreover, the prognostic value of high CD73 expression for the survival in lung cancer patients remains controversial: Although one study reported a correlation of high CD73 gene expression and improved overall survival of NSCLC patients (268) another study identified high CD73 protein expression as an independent prognostic marker for poor overall survival and shorter recurrence free survival in NSCLC (269). Here, NT5E is linked to non-small cell lung carcinoma.