Activating receptors in charge of tumor cytolysis in NK cells include NKG2D (Natural killer group2, member D), DNAM-1(DNAX accessory molecule-1), and NCR (Natural Cytotoxicity Receptors, NKp30, NKp44, NKp46) while KIR (Killer inhibitory receptors) and CD94-NKG2 heterodimers serve as inhibitory receptors (25, 26). The gene discussed is KLRK1; the disease is neoplasm.