miRNA-137-mediated ESRRA mRNA degradation contributes to the impaired proliferative and migratory capacity of breast cancer (BCa) cells as well as that of placenta trophoblast cells through reduced expression of the ERRα-regulated gene WNT11. miR-125a, by targeting ESRRA mRNA, reduces the proliferation and invasion of oral squamous cell carcinoma cells. This evidence concerns the gene ESRRA and breast carcinoma.