Besides converting EGF (114), the peripheral immune mediator found in the Pardo 2017 study of children with autism (102), ADAM17 converts the other cytokine mediators of autism found in the Pardo study: IL-15 (119), FLT3 (120), CX3CL1(121), and CXCL8 (122). The gene discussed is IL15; the disease is autism.